COMPOSITION:
Tylosin phosphate equivalent to tylosin base 15.0 g
Excipients up to 100 g
It is active againstChlamidia spp. as well. Tylosin does not act antimicrobially directly on the bacteria of the family Enterobacteriaceae E. coli, Salmonella spp., but reveals anantiadhesive activity (hindering their adhesion on the intestinalvili, their penetration through the intestinal mucous membrane and impeding their colonization's phase as well).
Tylosin proves also an anticoccidial activity mostly against Eimeriatenella. It also improves weight gain and feed conversion efficiency.
Applied orally, the antibiotic is absorbed by the gastro-intestinal tract not so intensively in comparison with the tartrate, but it penetrates in the target organs and tissues.
Excretion is mainly through urine and bile, milk (in lactating animals) and eggs (in egg-producing poultry).
It is compatible with tetracycline, sulphonamides, spectinomycin and the common dietary components of the feeds.
Orally, well homogenized into the feed.
In order to reach uniform homogenization with feed, it is recommended to mix the measured quantity of the preparation (calculated on the basis of the prescribed dose) on stages in the following order: up to 10 kg feed; up to 100 kg feed; and up to 1000 kg feed.
Breeder;200gm- 500gm
Excipients up to 100 g
PHARMACOLOGICAL ACTION:
Tylosin is a macrolide antibiotic with a bacteriostatic effect (inhibiting the synthesis of the bacterial proteins) against Gram-positive and some Gram-negative microorganisms Streptococcus spp., Staphylococcus spp., Erysipelothrixspp., Corynebacterium spp., Brachyspira, Serpulina (Treponema) hyodysenterae, Borrelia, Spirochaeta spp.,Campylobacter (Vibrio) coli, Pasteurella spp., Brucella spp., Ricketsia spp., Mycoplasma spp., some large viruses, including also some anaerobic microorganisms (Fusobacterium spp., Bacteroides spp.), etc.It is active againstChlamidia spp. as well. Tylosin does not act antimicrobially directly on the bacteria of the family Enterobacteriaceae E. coli, Salmonella spp., but reveals anantiadhesive activity (hindering their adhesion on the intestinalvili, their penetration through the intestinal mucous membrane and impeding their colonization's phase as well).
Tylosin proves also an anticoccidial activity mostly against Eimeriatenella. It also improves weight gain and feed conversion efficiency.
Applied orally, the antibiotic is absorbed by the gastro-intestinal tract not so intensively in comparison with the tartrate, but it penetrates in the target organs and tissues.
Excretion is mainly through urine and bile, milk (in lactating animals) and eggs (in egg-producing poultry).
It is compatible with tetracycline, sulphonamides, spectinomycin and the common dietary components of the feeds.
INDICATIONS:
For prevention and treatment of infections caused by tylosin-sensitive pathogenic microorganisms - mycoplasmosis, chronic respiratory disease, and infectioussynovitis in chickens and turkeys; Infectious sinusitis in turkeys; spirochetosis (borreliosis) in chickens; dysentery in pigs; for prevention of liver abscesses (caused by Spherophorusnecrophorus and Corynebacteriumpyogenes) in calves for fattening.CONTRA-INDICATIONS:
Tylosin must not be applied in lactating animals, the milk of which is intended for consumption or for technological processing. It must not be given to laying hens in poultry farms, which produce eggs for consumption (its use in stock layers is not contraindicated). It must not be included in compositions containing more than 2% of bentonite.MODE OF ADMINISTRATION:
Orally, well homogenized into the feed.
In order to reach uniform homogenization with feed, it is recommended to mix the measured quantity of the preparation (calculated on the basis of the prescribed dose) on stages in the following order: up to 10 kg feed; up to 100 kg feed; and up to 1000 kg feed.
DOSAGE:
Layer; 500gm -1kgBreeder;200gm- 500gm